CORRECTION: P1300- not P0300.......4.0L Bosche engine. I have codes P1300, P0305, P0307, p1319 with a blinking SES Light. Sometimes the light doesn't flash, just stays on. I have replaced the plug wires and plugs and cleaned the air filter trying to fix this, but still same trouble. Somewhat smooth idle, but not smooth acceleration. Anyone have any suggestions?

 

I suspect it is the coil. I had to change plugs, wires and coil. I got a coil pack from Advance Auto and changed it last February and it has not missed a lick since then.

 

I was leaning towards replacing the coils next or the MAF. Anyone else have any other ideas? I've also ran 2 cans of seafoam through the the fuel to no avail.

 

I've seen a bad or failing O2 sensor trigger misfires without causing any typical O2 sensor codes. I suspect that here because the two misfiring cylinders are both on the same side of the engine but 5 and 7 are on separate coils.

Coils can fail, but that's relatively rare on DIIs, plus the probability of both coils failing at about the same time seems remote. I'd be more likely to suspect the coils if paired cylinders were misfiring (e.g. 5 and 8 or 7 and 4). Since the two misfiring cylinders are next to each other a failed headgasket could also be causing the problem.

Try swapping upstream O2 sensors from side to side and see if the problem moves to the even-numbered cylinders. I'd try that before buying and installing coils.

 

I would do this today and move on to the next item of agenda if it does not work. Avoid running the engine for extended time as the blinking SE light is signaling catalyst-damaging misfires! You will ruin the catalytic converters and whatever else.
I didn't think O2 sensors could cause misfires but I also haven't had trouble with mine as of yet. If you must replace any sensors, buy OEM BOsch. Cheap, aftermarket parts won't work with BOsch ECU most of the time- plenty of threads on that topic.